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How Saffron 2020TM works for maitaining eye health?

Eye health and visual performance can decline over the years in part from low levels of specific nutrients and oxidative damage to the retina caused by free radicals, smoking, or exposure to high levels of light either from sunlight or computer monitor. We can benefit from a daily intake of special antioxidants and natural carotenoids to help protect our eyes from photooxidative damage and oxidative stress.

Saffron 2020TM is a special eye health nutritional supplement formulated with antioxidant ingredients that can regulate cellular pathways, scavenge free radicals, and protect DNA, proteins and lipids from oxidative damage.

Saffron 2020TM is formulated to help protect the lens and retina of eye from oxidative damage and photooxidative stress, which are the risk factors involved in deterioration of retinal cells and macula of the eye. Degeneration of macular cells can lead to gradual loss of vision over the years.

Function of Ingredients in Saffron 2020TM

Saffron 2020TM is the only product in the market that contains the following ingredients for optimal eye health:


macular degeneration saffron supplement with lutein and resverarol eye health, eyesight Saffron 2020  for eye health

Saffron is an ancient spice that has been used for millennia across Europe and Asia. Saffron stigma powder is derived from saffron crocus (Crocus sativus), and has been used to promote health. The carotenoids crocin and crocetin with antioxidant potential are found at biologically high concentrations in saffron.

Crocin has structural resemblance to lutein/zeaxanthin, and can help suppress light stress, and may help the retina recover from photo-oxidative damage. A recent research in Europe showed that patients with dry form of age-related macular degeneration (dry AMD) showed improvements in their vision after taking saffron pills for just three months.

According to recent research: “…saffron activates mechanisms of self-defence and self-repair in the retina of the eye protecting it against oxidative damage. Saffron restores some of the lost vision, and then stabilizes retina against further degeneration, which is the classic cause of development and progression of age-related macular degeneration (AMD).”

The clinical and laboratory results on beneficial effects of saffron to ameliorate ocular oxidative stress, and its potential for modulating cellular pathways in retina provided strong rationale for including saffron in our new nutritional supplement for AMD and general eye health.  Saffron 2020TM formula contains 20mg of highest quality saffron per capsule for regular daily intake.


Resveratrol is a dietary polyphenolic phytoalexin, a naturally occurring compound derived from the skin of grapes, found in red wine and several plants including peanuts and mulberries. Resveratrol mimics the ability of dietary restriction to delay age-related effects in mammals. The so-called French paradox is likely attributable to the biological properties of resveratrol. Large numbers of studies have demonstrated that resveratrol has protective effects on biological processes. 
Resveratrol may help counteract oxidative stress by inducing activity of enzymes such as superoxide dismutases-1 (SOD-1), catalase, and heme oxygenase-1 (HO-1) that are involved in scavenging hydrogen peroxide, a known element in oxidative damage.  Saffron 2020TM contains Polygonum plant extract equivalent to 100mg trans-resveratrol per capsule.

Lutein and Zeaxanthin:

macular degeneration saffron supplement with lutein and resverarol, eye health eyesight

Saffron 2020TM contains 10mg natural lutein and 2mg zeaxanthin from marigolds flowers.

Lutein and zeaxanthine are pigments also found in dark-green leafy vegetables, such as spinach, kale, broccoli, and in sweet corn. These carotenoids are important for retina function and health of macula of the eye responsible for central and fine vision. It is widely reported that low dietary intake of lutein and zeaxanthin is associated with higher risk of developing age-related macular degeneration.

It is important to remember that our body cannot synthesise lutein and zeaxanthin, and they need to be supplied through our diet or by nutritional supplementation. The level of these pigments in our eyes can decline over the years despite following a healthy diet, and it can be difficult to consume enough lutein and zeaxanthin to maintain the levels needed. Fortunately, serum and retinal levels of these important carotenoids can be modified by increasing dietary intake or by nutritional supplementation.

Vitamin A:

Vitamin A is a well characterised and recognized lipid soluble nutrient, which helps maintain normal vision and mucous membranes. Retinal is the active form of vitamin A in the body that is involved in photochemical reactions in the retina and is needed for normal vision, particularly for night vision, which can be affected over the years by changes of aging.

Vitamin B2:

Vitamin B2, also known as riboflavin, is a water soluble vitamin that is involved in a wide variety of metabolic pathways, including the biosynthesis and catabolism of amino acids, fatty acids and carbohydrates. Riboflavin has an important role as a coenzyme in energy-yielding metabolism, and contributes to normal metabolism of iron. Riboflavin has antioxidant properties involved in protecting cellular components from oxidative damage. Riboflavin deficiency can cause opacity of the lens, burning and itching of the eyes, photophobia, and a loss of visual acuity.
Riboflavin is a coenzyme that can help maintain normal vision.

Vitamin C:

Vitamin C: There have been many reports on eye health benefits of vitamin C and vitamin E in combination with zinc. Saffron 2020TM is a rich source of vitamin C, which is a water soluble antioxidant vitamin that helps protect DNA, proteins and lipids from the oxidative damage caused by free radicals. Additionally, vitamin C contributes to normal energy-yielding metabolism and helps maintain physical health.

Vitamin E:

Vitamin E is a potent biological antioxidant that is thought to have functional importance in maintaining cellular membrane integrity. Vitamin E has central role in protection against free-radical induced cellular damage. Vitamin E protects poly unsaturated fatty acids of cells by scavenging free radicals. Dietary intake of vitamin E is known to protect DNA, protein and lipids from oxidative damage. Free radical damage has been implicated in a number of degenerative and age-related processes.


Zinc There is established relationship between the dietary intake of zinc and normal DNA synthesis and cell division, protection of DNA, proteins and lipids from oxidative damage. Zinc is involved in maintenance of normal vitamin A metabolism, and maintenance of normal vision. "In retina and retinal pigment epithelium, there is evidence that zinc can modify photoreceptor plasma membranes, regulate the light-rhodopsin reaction, modulate synaptic transmission and serve as an antioxidant" (EFSA Journal, 2009: 7(9) 1229). 

Zinc is a cofactor for the potent antioxidant enzyme superoxide dismutase, which helps to protect cellular components from oxidative damage by neutralising free radicals. Zinc is an antioxidant micronutrients and a cofactor involved in activity of more than 200 enzymes such as alcohol dehydrogenase, DNA polymerase and RNA polymerase.


Copper: Dietary intake of copper contributes to protection of DNA, proteins and lipids from oxidative damage, and contributes to normal energy-yielding metabolism and iron transport.


Saffron 2020TM is formulated with balanced and sensible levels of important eye health nutrients, and is suitable for reoutin daily intake by people concerned about health of their eyes.

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Selected References

-EFSA Journal 2010; 8(10): 1754 & 1814 & 1815 & 1816 & 1819.
-EFSA Journal 2009; 7(9): 1211; 1229
-Ophthalmic Res 2010;44:166–172
-Invest Ophthalmol Vis Sci. 2010, 51:6118-6124
-Mol Vis. 2010, 16:1801-22.
-Optometry 2009, 80, 695-701
-Optometry 2007, 78: 213-219
-Exp Eye Res 2007, 84:718-728
-Age-related eye disease study research group (AREDS report no. 8). Arch Ophthalmol 2001;119(5): 1417-1436



Antioxidants, plant extracts and natural carotenoids in Saffron 2020TM can help the eye by:

-Protecting against oxidative damage
-Modulating cellular pathways with important retinal cell-protective and recovery functions for optimal macular structure and performance.

Ingredients in Saffron 2020TM work together and may influence the risks involved in early-stage age-related visual problems.


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